Computational genomics, Bioinformatics, NGS analysis and method development, Somatic mutation analysis, Single cell genomics
Education
2009-2014: Ph.D., Department of Bio and Brain Engineering, KAIST, Korea
2008-2009: M.S., Department of Bio and Brain Engineering, KAIST, Korea
2004-2008: B.S., Department of Bio and Brain Engineering, KAIST, Korea
Experience
2021-present: Assistant Professor, Department of Biological Sciences, Sungkyunkwan University, South Korea
2017-2021: Postdoctoral Research Fellow, Boston Children’s Hospital and Harvard Medical School, Boston, MA
2014-2018: Postdoctoral Researcher, Yonsei Biomedical Science Institute, Yonsei University College of Medicine, South Korea
Journal Articles
(2023)
CanISO: a database of genomic and transcriptomic variations in domestic dog (Canis lupus familiaris).
BMC GENOMICS.
24,
1
(2022)
Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders.
NATURE COMMUNICATIONS.
13,
1
(2022)
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
NATURE GENETICS.
54,
10
(2022)
Somatic genomic changes in single Alzheimer’s disease neurons.
NATURE.
604,
7907
(2022)
Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain.
CANCER DISCOVERY.
12,
1
(2022)
Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity.
Nature Aging.
2,
8
